KMID : 0370219860300050232
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Yakhak Hoeji 1986 Volume.30 No. 5 p.232 ~ p.237
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Synthesis and Antibiotic Activities of Poly (acrylic acid) Modified ¥â-Lactam Cyclics
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Abstract
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A series of modified poly(acrylic acid)¢¥s containing different levels of 6-aminopenicillanic acid (6-APA), 7-aminocephalosporanic acid (7-ACA) and 6-(D-(?)-a-aminophenyl acetamidoj penicillanic acid (ampicillin) as pendant groups were prepared. Antibiotic activities of the newly prepared drugs were examined against the various gram-positive and gram-negative bacteria. It was found that ampicillin modified composition posses antibiotic activities against the gram-negative as well as the gram-positive bacteria.
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KEYWORD
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